Benzene, 1-fluoro-2-methoxy-4-methyl-5-nitro- (cas 63762-81-2) SDS(Safety Data Sheet) /MSDS download (2023)


1.1 GHS Product identifier

Product name 1-fluoro-2-methoxy-4-methyl-5-nitrobenzene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details


1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

no data available

2.2 GHS label elements, including precautionary statements

Pictogram(s) no data available
Signal word

no data available

Hazard statement(s)

no data available

Precautionary statement(s)

no data available


no data available


no data available


no data available

2.3 Other hazards which do not result in classification

no data available

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
1-fluoro-2-methoxy-4-methyl-5-nitrobenzene 1-fluoro-2-methoxy-4-methyl-5-nitrobenzene 63762-81-2 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state no data available
Colour no data available
Odour no data available
Melting point/ freezing point no data available
Boiling point or initial boiling point and boiling range no data available
Flammability no data available
Lower and upper explosion limit / flammability limit no data available
Flash point no data available
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility no data available
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure no data available
Density and/or relative density no data available
Relative vapour density no data available
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods


The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: no data available IMDG: no data available IATA: no data available

14.2 UN Proper Shipping Name

ADR/RID: no data available
IMDG: no data available
IATA: no data available

14.3 Transport hazard class(es)

ADR/RID: no data available IMDG: no data available IATA: no data available

14.4 Packing group, if applicable

ADR/RID: no data available IMDG: no data available IATA: no data available

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
1-fluoro-2-methoxy-4-methyl-5-nitrobenzene 1-fluoro-2-methoxy-4-methyl-5-nitrobenzene 63762-81-2 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Not Listed.
EC Inventory Not Listed.
United States Toxic Substances Control Act (TSCA) Inventory Not Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Not Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Not Listed.
Vietnam National Chemical Inventory Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Not Listed.

16.Other information

Information on revision

Creation Date Aug 18, 2017
Revision Date Aug 18, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website:
  • HSDB - Hazardous Substances Data Bank, website:
  • IARC - International Agency for Research on Cancer, website:
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
  • CAMEO Chemicals, website:
  • ChemIDplus, website:
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website:
  • Germany GESTIS-database on hazard substance, website:
  • ECHA - European Chemicals Agency, website:
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.


Does the SDS list hazardous ingredients? ›

The SDS includes information such as the properties of each chemical; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the chemical.

Is 1 methyl 4 nitro benzene safe? ›


* Benzene, 1-(Chloromethyl)-4-Nitro- can affect you when breathed in. * Contact can irritate the skin and eyes. * High levels may interfere with the ability of the blood to carry Oxygen causing headache, fatigue, dizziness, and a blue color to the skin and lips (methemoglobinemia).

What are the toxicity and hazards of 2 methyl 2 butene? ›

Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. May cause lung damage. Inhalation: May cause respiratory tract irritation.

Is SDS available for all chemicals? ›

Finding the right document should be easy. Every chemical manufacturer or importer must provide an SDS for any hazardous materials they sell, and OSHA requires that all workplaces in the United States keep an SDS for every hazardous chemical onsite.

Can you use a hazardous product without a SDS? ›

Yes. Employers will be required to make sure that all hazardous products (as defined by the Hazardous Products Regulations have an up-to-date SDS when it enters the workplace.

Where can I get SDS sheets? ›

To obtain SDS, get them from the manufacturer.
  • They may be sent with the chemical order (paper copy or e-mail attachment).
  • Otherwise, go to the manufacturer's website and download it or request a copy.

Is benzene cancerous? ›

The Department of Health and Human Services has determined that benzene is a known carcinogen (can cause cancer). Both the International Agency for Cancer Research and the EPA have determined that benzene is carcinogenic to humans. Exposure to benzene may be harmful to the reproductive organs.

What are the side effects of nitro benzene? ›

At low nitrobenzene concentrations, symptoms include fatigue, weakness, dyspnea, headache, and dizziness. At higher concentrations, depressed respiration, bluish-gray skin, disturbed vision, and coma may occur.

What is an unsafe level of benzene? ›

Basis for revised IDLH: The revised IDLH for benzene is 500 ppm based on acute inhalation toxicity data in humans [Gerarde 1960]. [Note: NIOSH recommends as part of its carcinogen policy that the "most protective" respirators be worn for benzene at concentrations above 0.1 ppm.

Is 2 mercaptoethanol a carcinogen? ›

OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.

What are the hazards of 2 mercaptoethanol? ›

2-Mercaptoethanol is extremely toxic if swallowed or inhaled and can be fatal if absorbed through the skin. It is corrosive and can cause severe burns to the skin and eyes. It is also a combustible liquid. This compound is extremely toxic to aquatic life and has long-lasting effects in the environment.

What are the hazards of methyl 2 nitrobenzoate? ›

Caution! May cause eye and skin irritation. May cause respiratory and digestive tract irritation. The toxicological properties of this material have not been fully investigated.

Which SDS categories are most hazardous? ›

Category 1 is always the greatest level of hazard (that is, it is the most hazardous within that class). If Category 1 is further divided, Category 1A within the same hazard class is a greater hazard than category 1B. Category 2 within the same hazard class is more hazardous than category 3, and so on.

Do you need SDS for household chemicals? ›

Answer: Yes. If those products on the shelves meet the definition of 'hazardous' found in the hazard communication law, 1910.1200 (d)-(d)(3)(ii). OSHA has 14 letters of interpretation on .

What products are exempt from SDS? ›

Exempt items generally include food or alcoholic beverages which are sold, used, or prepared in a retail establishment (such as a grocery store, restaurant, or drinking place), and foods intended for personal consumption by employees while in the workplace.

Are MSDS still acceptable? ›

Response: Yes, as long as the MSDS is compliant with the former Hazard Communication standard, HCS 1994.

Do SDS expire after 5 years? ›

A Safety Data Sheet shall be reviewed at least every 3 years. Records of SDS updates such as content, date, and version revision, shall be kept for 3 years.

What is the difference between SDS and MSDS? ›

MSDS (Material Safety Data Sheet) is now called an SDS (Safety Data Sheet). The purpose of both MSDS and SDS documents remains unchanged and is to list the information pertaining to the occupational health and safety for the various uses of the substances and products.

How many years do you keep SDS sheets? ›

OSHA standard, 29 CFR 1910.1020, Access to employee Exposure and Medical Records defines "employee exposure records" to include material safety data sheets. The standard requires all employee exposure records to be maintained for at least 30 years.

How much does an SDS cost? ›

A Safety Data Sheet doesn't cost you anything, as long as your supplier can provide one. However, if that's not the case you'll need to use an SDS authoring service.

Are SDS sheets public information? ›

The public has a right to MSDS data upon request. They must be written in English and contain: the name of the chemical (same as on the label) the chemical and common names of the substance.

What cancers does benzene cause? ›

IARC classifies benzene as “carcinogenic to humans,” based on sufficient evidence that it causes acute myeloid leukemia (AML). IARC also notes that benzene exposure has been linked with acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin lymphoma.

How long does benzene stay in your body? ›

Benzene is converted to chemical products, called metabolites, in the liver and bone marrow. Some of the harmful effects of benzene exposure are caused by these metabolites and not benzene itself. Most of the metabolites of benzene leave the body in the urine within 48 hours after exposure.

Is benzene a cause of leukemia? ›

Long-term benzene exposure can harm your bone marrow and blood cells. Exposure to benzene, a known carcinogen, may cause abnormalities in the DNA that controls the development of blood cells in your bone marrow. This, in turn, can damage your immune system and raise the risk of developing leukemia.

What organ does benzene affect? ›

Benzene works by causing cells not to work correctly. For example, it can cause bone marrow not to produce enough red blood cells, which can lead to anemia. Also, it can damage the immune system by changing blood levels of antibodies and causing the loss of white blood cells.

What happens if you take nitro and you don't need it? ›

Taking more of this drug than you need can lead to tolerance. This means that, over time, the drug may not work as well to treat your chest pain. Dissolve your dose under your tongue or in your cheek at the first sign of chest pain.

What are the dangers of nitro compounds? ›

A number of its metallic salts are also dangerous fire and explosion hazards. Following ingestion of a few grams of picric acid, which has an intensely bitter taste, acute gastroenteritis, toxic hepatitis, nephritis, haematuria and other urinary symptoms may occur.

What is an acceptable level of benzene? ›

OSHA: The legal airborne permissible exposure limit (PEL) is 1 ppm averaged over an 8-hour workshift and 5 ppm, not to be exceeded during any 15-minute work period.

What are the symptoms of benzene poisoning? ›

Generally, symptoms of CNS toxicity are apparent immediately after inhalation of high concentrations of benzene (3,000 ppm for 5 minutes), and 30 to 60 minutes after ingestion. Mild effects include headache, lightheadedness, dizziness, confusion, nausea, impaired gait, and blurred vision.

Do all dry shampoos have benzene? ›

Recent Study Confirms Many Popular Dry Shampoos Contain Benzene, a Known Carcinogen. Richard Console, Jr. Console and Associates, P.C. Recently, an independent laboratory conducted a series of tests on several different dry shampoos, finding that 70% of the tested products contain benzene.

What does not have to be listed on the SDS? ›

Exempt items generally include food or alcoholic beverages which are sold, used, or prepared in a retail establishment (such as a grocery store, restaurant, or drinking place), and foods intended for personal consumption by employees while in the workplace.

What 3 products are excluded from SDS? ›

Some types of products are excluded from labeling and SDS requirements because they're regulated by other laws. Three types of excluded products are: Consumer products, explosives, and pesticides.

What must be listed on hazardous chemical inventory? ›

Include the following in your chemical inventory:
  • Aerosol products.
  • Compressed gases.
  • Flammables and combustibles.
  • Oxidizers.
  • Organic peroxides.
  • Poisons not included in the above categories.
  • Corrosives.
  • Controlled Substances (Drug Enforcement Agency listed drugs)

What is SDS in hazardous material? ›

A Safety Data Sheet (SDS) (formerly MSDS) is designed to provide both workers and emergency personnel with the proper procedures for handling or working with a particular substance.

How can I get MSDS sheets for free? ›

SDS Manager offers a free online service available to everyone, where you can find and download Safety Data Sheets for your business. Our online SDS service is always available to you.

What chemicals need SDS sheets? ›

OSHA only requires safety data sheets (SDSs) for hazardous products or chemicals. GLT Products, along with other manufacturers are not required to provide SDSs for non-hazardous materials or products. OSHA has left it up to the producer whether or not they should provide SDSs for non-hazardous materials.

Is a Category 1 substance more hazardous than Category 2? ›

Category 1 is always the greatest level of hazard within its class. – If Category 1 is further divided, Category 1A within the same hazard class is a greater hazard than category 1B. Category 2 within the same hazard class is more hazardous than Category 3, and so on. There are a few exceptions to this rule.

What are 3 common household SDS items? ›

Safety Data Sheets also referred to as SDS is mandatory for everybody who produces manufactures and sells a chemical product. This would be things like shampoo, deodorant, toothpaste and your cleaning supplies.

What are incompatible materials on SDS? ›

Incompatible materials

Classes of chemicals (e.g., acids, fluorides, chlorides) or specific substances that could react to produce a hazardous situation should be disclosed. Products that are corrosive to metals, the degree of corrosivity and the affected metals should be disclosed.

How many workers in the US are exposed to hazardous chemicals? ›

The Occupational Safety and Health Administration (OSHA) estimates that about 32 million workers in more than 3.5 million workplaces are regularly exposed to hazardous chemicals.

What three items must be covered in a written security plan relating to hazardous materials? ›

At a minimum, a security plan must include the following elements: personnel security, unauthorized access, and en route security.

Do you have to keep old SDS sheets? ›

So, how long do you keep MSDS sheets exactly? SDS files are considered employee exposure records. Even when a chemical is no longer in use, the SDS should be archived/maintained for 30 years.

What are 3 types of hazards section 2 of SDS? ›

SDS Section 2: Precautionary measures you should take to safely handle chemicals. Handling chemicals improperly could cause physical, health, and environmental hazards in your workplace.

Will SDS replace MSDS? ›

The new standard — the SDS, which officially replaced the MSDS — saw many improvements in consistency and format and is the ongoing standard for health and safety information on hazardous chemicals.

What is the difference between SDS and MSDS sheets? ›

The main difference between an MSDS and an SDS is the standardized formatting. All SDSs follow the GHS's 16 section formatting, while MSDSs could come in many different formats depending on the organization. Beyond that, they aim to convey the same information regarding chemical hazards.


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